New computational microscopy technique offers a more direct route to sharp images

Concept of angular ptychographic imaging with closed-form method (APIC) and comparison between the reconstruction process of APIC and Fourier ptychographic microscopy (FPM). Credit: Nature communication (2024). DOI: 10.1038/s41467-024-49126-y For hundreds of years, the brightness and magnification of microscopes were ultimately limited by the physical properties of their optical lenses. Microscope makers pushed those limits by … Read more

Scientists adapt the astronomy method to blur microscopy images

Detecting anomalous wavefronts in fluorescence microscopy. Credit: Optics (2024). DOI: 10.1364/OPTICA.518559 A team led by researchers at HHMI’s Janelia Research Campus has adapted a class of techniques used in astronomy to defocus images of distant galaxies for use in the life sciences, giving biologists a faster and cheaper way to get clearer and sharper images. … Read more

Scientists adapt the astronomy method to blur microscopy images

This article was reviewed according to Science fact checked peer-reviewed publication trusted source proofread OK! Detecting anomalous wavefronts in fluorescence microscopy. Credit: Optics (2024). DOI: 10.1364/OPTICA.518559 × close to Detecting anomalous wavefronts in fluorescence microscopy. Credit: Optics (2024). DOI: 10.1364/OPTICA.518559 A team led by researchers at HHMI’s Janelia Research Campus has adapted a class of … Read more