‘A History of Contact’: Geneticists Rewrite the Story of Neanderthals and Other Early Humans

Detection of modern human-to-Neanderthal gene flow (H→N) and its consequences. Modern human-to-Neanderthal admixture causes a local increase in heterozygosity in the Neanderthal genome, a feature that enabled approaches to quantify and detect introgressed sequences. We used modern human-introgressed sequences in the Neanderthal genome to refine estimates of Neanderthal ancestry in contemporary humans by decomposing IBDmix-detected … Read more