The ‘gene deserts’ that unravel the mysteries of disease

Getty Images Mutations in these regions of so-called ‘junk’ DNA are increasingly linked to a range of diseases, from Crohn’s disease to cancer. Since the Human Genome Project was declared complete in 2003, scientists have been trying to pinpoint new areas among the three billion letters of our genetic code that may play a crucial … Read more

Breakthrough in gene editing promises to boost the fight against disease

Unlock the Editor’s Digest for free Roula Khalaf, editor of the FT, selects her favorite stories in this weekly newsletter. Scientists have broken a new frontier in the rapidly evolving field of gene editing with the discovery of a way to program the recombination and rearrangement of DNA. The new technique promises to expand the … Read more

Beyond CRISPR: seekRNA offers a new path for precise gene editing

This article was reviewed according to Science fact checked peer-reviewed publication trusted source proofread OK! IS1111 and IS110 family functions. Credit: Nature communication (2024). DOI: 10.1038/s41467-024-49474-9 × close to IS1111 and IS110 family functions. Credit: Nature communication (2024). DOI: 10.1038/s41467-024-49474-9 Scientists at the University of Sydney have developed a gene-editing tool with greater accuracy and … Read more

Breakthrough in biomedicine: complete gene insertion now possible in human cells

SciTechDaily

Researchers at the Broad Institute have improved gene editing to efficiently insert entire genes into human cells, offering potential for single-gene therapies for diseases such as cystic fibrosis. This method combines prime editing with new enzymes to improve editing efficiency, potentially revolutionizing gene therapy. The gene editing technique uses primary editors and advanced enzymes known … Read more

Gene editing strikes oil: High-efficiency Camelina revolutionizes biofuels

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Artist’s rendering of the effect of editing all six copies of the TT8 gene in Camelina sativa. Seeds with inactivated TT8 genes (right) show a yellow color, reduced thickness of their seed coat and an accumulation of almost 22% more oil than wild seeds (left). Credit: Valerie Lentz/Brookhaven National Laboratory Scientists have increased oil production … Read more

How baby boomers really had it easy

Boomers were twice as likely to buy a home earlier in life, data shows Home ownership has shifted to older generations over the past twenty years Stop eating avocado on toast, cancel Netflix and work harder. That’s the jokey advice commonly parroted as the solution to Gen Z’s homeownership problems. But stagnant wages and rising … Read more

Improved prime editing system enables gene size editing in human cells at therapeutic level

This article was reviewed according to Science fact checked peer-reviewed publication trusted source proofread OK! Credit: AI-generated image × close to Credit: AI-generated image Scientists from the Broad Institute of MIT and Harvard have improved a gene-editing technology that is now capable of inserting or replacing entire genes in the genomes of human cells efficiently … Read more